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As the 2023 NFL season continues to unfold, the excitement and unpredictability only seem to intensify. Last week’s games featured a number of explosive touchdowns, along with a few unexpected upsets. The NFL’s knack for delivering thrilling moments is unparalleled, but it’s also a goldmine for those with a keen eye for the betting opportunities hidden within the chaos.

As we look ahead to the NFL’s Week 6 schedule, there are several appealing betting matchups to consider ahead of Sunday. From hard-fought divisional battles to high-scoring double-digit spreads, Week 6 has something for every NFL bettor. You can find all of the NFL Week 6 betting odds at Bovada Sportsbook, along with a treasure trove of enticing props and futures to elevate your NFL experience.

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In this week’s NFL betting article, we’ll provide you with the essential knowledge to make sharp wagers this Sunday and beyond. From injury updates to the latest betting trends, we’ve got you covered. So grab your playbook, sharpen your instincts and let’s seize the NFL betting opportunities that await in Week 6!

Atlanta’s Home Cooking

The Falcons delivered one of last week’s most thrilling victories, kicking a game-winning field goal as time expired to defeat the Houston Texans, 21-19. The win is nothing new for the fans in Atlanta, who have now won five straight games at Mercedes-Benz Stadium. Want an even more impressive stat? Falcons quarterback Desmond Ridder is undefeated at home in both his college and NFL career! The mobile passer went a perfect 26-0 at home during his time with the Cincinnati Bearcats and with wins in his first 5 home starts in Atlanta, Ridder is now 31-0 at home as a starter in college and the NFL.

This incredible streak will be tested yet again in Week 6, with the 3-2 Falcons currently listed as 2.5-point home betting favorites against the 2-3 Washington Commanders. After winning their first two games of the season, Washington has now lost three straight, including a particularly ugly defeat last week versus the Bears. With momentum clearly on Atlanta’s side, you may want to bet the home team in this Sunday matchup.

Divisional Duel

With both teams currently tied atop the AFC South standings at 3-2, the Week 6 divisional matchup between the Indianapolis Colts and Jacksonville Jaguars could end up having major implications for this year’s playoff picture. The Jaguars are currently available as 4.5-point betting favorites and will be looking to stay hot after winning back-to-back games in London, while the Colts will be out for revenge after losing to the Jags at home in Week 1.

The good news for Indianapolis is that they now have star running back Jonathan Taylor back on the field after a lengthy contract dispute. The bad news is that rookie quarterback Anthony Richardson suffered a shoulder injury against Tennessee and will likely be out for four to six weeks. Backup quarterback Gardner Minshew will fill in under center for the Colts and will also be seeking revenge as he goes up against the franchise that drafted him back in 2019. While the game is in Jacksonville, the Jaguars may be a bit travel weary after spending the past two weeks overseas. With Indy’s moneyline odds currently sitting at +175, consider betting on the Colts to pull off the upset.

Cowboys Back on the Horse

After last week’s 42-10 thumping at the hands of the San Francisco 49ers, the Dallas Cowboys will look to get back on track in Week 6 as they visit the Los Angeles Chargers on Monday Night Football. While Dallas was completely dominated in their last game, it may have created some solid betting value as the Cowboys are now just 2-point favorites over the Chargers. Dallas should have a much easier time versus a Chargers team that gives up the second-most yards per game in the NFL (404 YPG).

Say what you will about the Cowboys, but this franchise loves the spotlight. Dallas is no stranger to the bright lights of prime time football and have gone 10-1 in their last 11 Monday Night Football road games. They’re 13-7 ATS in their previous 20 road games overall, although you can expect the “home” crowd in Los Angeles to be littered with Cowboys fans. Dallas has also been great at bouncing back from adversity; in their last 11 games following a loss, the Cowboys have gone an impeccable 10-1 against the spread (ATS).

Jefferson on IR

It may have taken a staggering 347 days, but the Chicago Bears are once again winners in the NFL. With last week’s 40-20 victory over the Washington Commanders on Thursday Night Football, Chicago put an end to a franchise-record 14-game losing streak and enjoyed a rare bright spot in what has been a disappointing start to the season. Things haven’t been much better in Minnesota, as the Vikings are tied with the Bears at the bottom of the NFC North with a 1-4 record. These two teams will face off in Week 6, with Minnesota currently listed as 2.5-point road betting favorites and the total set at 44.5.

The big news in this matchup is the status of Minnesota’s Justin Jefferson, as the All-Pro receiver has been placed on IR with a hamstring injury and will miss the Viking’s next four games. This injury has led to a dip in the game total and provides us with a potentially lucrative betting opportunity on the over. The Vikings and Bears have two of the NFL’s worst defenses and it’s not hard to envision a ton of scoring by both offenses. It’s also worth noting that the Bears are the only team in the NFL to hit the over in all five games this season. With Minnesota quarterback Kirk Cousin still capable of moving the chains without Jefferson and Chicago’s offensive attack looking reinvigorated over the past couple of weeks, taking the over seems like a viable Week 6 betting strategy.